27 October 2020

OxyContin Abuse In The United States

The content of the previous chapter centered mostly around opioids and opioid-based medicines as a means to present the commonly abused branch of pharmaceuticals as exemplary of the issue of marketed substance overdoses. The present chapter will share the focus, this time containing a more detailed description, in order to provide the explanation for the previously portrayed problem, and to provide one with the basis for understanding not only the causes of opioid-based medicine addiction, but also similar issues with other types of pharmaceuticals (discussed more broadly in the final chapter).
In order to provide the best approach to comprehending the question correctly, it is necessary to begin with numbers.
The chart displayed below (obtained from the official website of Centers for Disease Control and Prevention (CDC)) discloses the number of various opioid-based medicines prescribed yearly in the United States.

 
According to the data, between the years 2010 to 2012, the numbers of submitted prescriptions seem to have reached their peak, decreasing steadily in the following years. It is substantial to notice that the statistics for the time of opioids being prescribed the most often correspond with the input from the graph included in the previous chapter regarding the highest number of deaths due to prescription opioids.
But the raw numbers alone do not fully illustrate such widespread issue. The featured map, originally published by Market Watch, cites the concentration of patients dependent and/or addicted to prescription opioids per state (years 2012 to 2014).

 
By studying the map, three patterns can be recognised. The density seems to be the highest (marked dark red and dark orange) in some of the most populated states, noticeably California and New York. However, the highest recorded figure for opioid dependence (both pathological and for medical reasons) remains in West Virginia, together with several other states (Kentucky, Tennessee, Louisiana); all of them have a considerably smaller number of inhabitants than the locations mentioned before. Furthermore, except for Nevada, they are all located in the east coast of the United States. Yet another indication that can be derived from the map suggests the issue to be of much less prevalence in the mid-country, notably in Wyoming, South Dakota, Nebraska, Kansas, and Iowa (as well as in Hawaii and Alabama).
Now that the data presented above has been detailed, the reason for the phenomenon must be identified as well. Is the given states being affected (or safe from) the opioid epidemic a purely coincidental occurrence, or is there a factor, or even a number of factors, that contribute to the problem and the lack of thereof in the specific areas?
For the purpose of presenting the question in a clear and easily understandable manner, one should start the analysis with the human factor, as those affected are the core focus of the issue.
 
The map included above depicts the United States population as divided by ethnicity. Noticeably, the states described as the most affected by prescription opiate addiction are mostly inhabited by white people of European descent (in regards of the “American” ethnicity: those are the Americans of overwhelmingly white European heritage that do not refer to themselves as e.g. Polish American or being a person of French, Czech, and Portuguese descent, but instead choose to identify as simply American, thus not entertaining the fact of the United States being a “nation of immigrants”). California and New York appear to be the exceptions, however this is due to the large populations of these areas: the states have subsequently 72.7 and 58.3 percent of inhabitants of Caucasian origin.
Besides the racial aspect, there are few more similarities that need to be touched on; the most significant ones can be found in the article Why does opioid dependence vary so dramatically by U.S. State? by Allesandra Malito and Quentin Fottrell (2018) of Market Watch.
The authors mention the poor financial situation of the inhabitants of certain states as one of the most important factors leading to opioid abuse. At first, such statement might seem contradictory – since developing prescription opiate addiction requires frequent use of the medicine, normally with dosages increasing over time, struggling financially should prevent the pathological behaviour, not prompt it. Malito and Fottrell puncture the discrepancy; it is the alternative ways of treatment that are expensive, or at least more expensive than opioid-based painkillers.

“Americans on a low income may not be able to afford alternative care or surgery, which effectively means they would have more need for opioid prescriptions to deal with chronic pain. Another problem: Some people may not be able to take time off work and/or may not be able to pay to travel to clinics for regular care.”

To illustrate the issue in a greater detail, and bring a compelling perspective to the question, essential to study and compare the average income in the areas influenced by opioid painkiller abuse, with those where the problem is not as severe.
The census provided by United States Census Bureau (USCB), covering the years 2013-2017, (USCB divides its directory of places ranked by household income for 56 areas – including five unincorporated territories of the United States, e.g. Guam Island, and Puerto Rico) positions the most affected state, West Virginia, as 51st (1st being the highest household income) – making it the most financially underprivileged of all states. Other areas concerned with a large scale of the issue, Louisiana, Kentucky, and Tennessee, were ranked subsequently 48th, 45th, and 42nd, further proving the point of the lack of money being one of the causes of pathological painkiller used.
To create a comparison, the states mentioned above as those with the least amount of opioid prescription addicts, rank at 4th (Hawaii), 20th (Wyoming), 22nd (Nebraska), 26th (Iowa), 30th (South Dakota), and 31st (Kansas).
Another point brought up by the authors of the article, is the correlation between the amount of time spent filling in a prescription, and the time that further examination or introducing the patients to alternative methods of treatment require. Clearly, prescribing a medicine (which, as acknowledged in the previous chapter, is usually the one the patient has known and used for the longest time, and trusts its properties) is a lot less time-consuming practice than recommending treatment based on the individual's specific needs and abilities (most of the time also financial). Such process might, paradoxically, steam from the doctor's desire to treat as many sufferers as possible – a prescription will help alleviate the pain at least temporarily for a large number of people, while focusing on a single case for a longer period of time is likely to prevent some of the patients from receiving even a short-lived relief. Malito and Fottrell call such system “drive-by appointments”.
Sadly, the problem with physicians being at least partially responsible for the opioid epidemic is not limited to just their lack of time – the lack of proper care and the absence of doctors themselves are also the deciding factors.
The authors quote Dr Akash Bajaj's analysis of the issue, which also connects it to the previous point:

“In less populated states like Kentucky and West Virginia, there is a tendency to practice more traditional pain management techniques, which may rely heavily on medications as this approach is quick, cheap and, in the short run, can be effective (...) However, as we have seen this problem can quickly spiral out of control due to the need to take more medication to achieve the same effect.” He insists that instead of practicing the "drive-by appointments", doctors should rather “(...) focus more on definitive therapy, identifying the problem and treating as specifically as possible, without medication management.”

Dr Bajaj also discloses another malpractice that can be observed among physicians, presumably the most vile one of those already mentioned in the chapter. He suggests that certain doctors might take advantage of their patients being reliant on opioid-based painkillers, whether because of their financial struggle, not being suggested any alternative treatment, or already developed physical and/or mental dependence, to assure the sufferers would need their service again. The doctor describes the process with an evident critique of it:

“There are some doctors who will indulge a patient’s desire for painkillers, which often take the form of opioids, in order to keep their practices afloat. This is not good for the patient or the practice. (...) Of course, this is not good for the patient or the practice and, thankfully, there has been a crackdown on such practices.”

As, after presenting the data, certain painkiller abuse appears to take on the most severe form in particular areas, most of the time linked together by the aspects of household income and ethnicity, with the situation worsened by medical malpractices, one cannot forget the places that do not necessarily meet the criteria for being at risk of facing the abuse (at least as long as the financial aspect is taken into consideration), yet a part of their inhabitants still suffers from prescription addiction.
Dr Bajaj, who works in California, thus presumably being familiar with the inconsistency, characterises its most probable cause:

“(...) it’s easier for patients to find opioids when there are more physicians to choose from. In more populated states like California (...) patients are more willing to doctor shop until they find someone willing to give them what they think they need. This is not only a violation of ethics, but can put the patient’s life in danger.”

However, keeping in mind the specifications of prescription abuse demonstrated by Malito and Fottrell, such analysis would imply that those already suffering from opioid dependence, would chose searching highly populated areas as a means of acquiring the medicine; them permanently residing in California or New York would not be the cause of their problem, but rather fuel it shall it already exist.
The authors, however, begin to clarify the inconsistency at the end of their article – more specifically, when they refer to Dr Bajaj's statement about “doctor shopping”.
In more populated areas the number of physicians is, undoubtedly, considerably bigger than in less inhabited states; consequently, the number of patients rises as well, but with more doctors to chose from they are generally not forced to wait for treatment, such as those in the areas where there are no alternatives. This situation eliminates the issue of “drive-by appointments”, allowing the doctors to focus on an individual and suggest various methods of therapy (even the costly ones – the average household income in California places the state at the 5th place, whereas New York ranks 15th).
Sadly, with one problem being solved, another seems to have occurred; doctors being able to pay the patient the appropriate amount of time, supposedly lowering the amount of opioids being prescribed, did not cause the number of white people from highly populated areas overdosing on prescription painkillers to decrease.
Thus, the cause of the problem appears to have no logical connection to any of the reasons presented by Malito and Fottrell – the arguments of low income, medical malpractice, and lack of medical centers are no longer.
The 2019 investigation by Joseph Friedman, David Kim, Todd Schneberk, Philippe Bourgois, Michael Shin, Aaron Celious, and David Schriger, Assessment of Racial/Ethnic and Income Disparities in the Prescription of Opioids and Other Controlled Medications in California, introduces the reader to an intriguing hypothesis that aims to answer the raised question. According to the authors, what propels the epidemic in the particular community, are not reasons of the affected living in a specific place, with certain living conditions; rather, it is the racial bias towards ethnicities other than Caucasian expressed by the doctors in charge.
One might yet again notice a discrepancy in such account. Had the physicians' decisions been fueled by racial antipathy towards a given group, in this instance, all except Caucasians, they would prescribe addictive substances to patients of ethnicities other than white – which, considering the racial component of the opioid epidemic, seems to be the exact opposite. While this perspective is legitimate, the authors suggest a contrasting approach to understanding the dilemma:

 “(...) Hispanic patients were 2 times less likely to receive analgesics following long bone fractures than white patients, after accounting for other factors. Similar discrepancies in pain medication prescribing were found for black patients relative to white patients. Recent studies have found that healthcare professionals often underestimate the pain of black patients when compared with white patients and that such racial/ethnic biases in the detection of pain are seen among healthcare professionals who report no explicit racial/ethnic biases. These gaps, coupled with decreased access to the healthcare system for many racial/ethnic minority groups, have led several authors to suggest that there is a national crisis of insufficiently medicated pain among minority communities in the United States. In light of a similar gradient in opioid overdose deaths, these disparities in opioid prescription may have played an accidental protective role in minimizing the opioid epidemic among minority communities.”

The detailing of the approach does, in fact, inform one of the existence of the issue, as well as helps recognise the reason for excuse for other ethnic groups being less likely to be affected by the epidemic. Nonetheless, the authors do not provide any interpretation as to why such bias would be held and executed by physicians (“the roots of this racial/ethnic phenomenon have not been adequately explained”).
The answer seems to be at least suggested in the 2017 interview Dr Andrew Kolodny gave for the National Public Radio:

“Something that we do know is that doctors prescribe narcotics more cautiously to their non-white patients. It would seem that if the patient is black, the doctor is more concerned about the patient becoming addicted, or maybe they're more concerned about the patient selling their pills, or maybe they are less concerned about pain in that population. But the black patient is less likely to be prescribed narcotics, and therefore less likely to wind up becoming addicted to the medication. So what I believe is happening is that racial stereotyping is having a protective effect on non-white populations.”

Kolodny's commentary grants a sensible resolution to the aforementioned hypothesis. The reason for such perception or prejudice in physicians remains the matter of discussion that would no longer center around prescription opioid abuse, however, assuming that the objective is valid, the painkiller abuse in highly populated areas that maintain a high household income appears to be logically justified.
Nevertheless, one should keep in mind, that even though Caucasians might be perceived as more responsible and less likely to be involved in drug abuse and trafficking by physicians, they should not be blamed for the practice; unless there is a legitimate, proven case of a white patient persuading the doctor to be prescribed a medicine for the reasons acknowledged above, no group can not be held accountable for the favouritism of other group (particularly if such bias is inclined to lead to a damaging outcome, indicating that Caucasians suffer the effects of the epidemic regardles of their financial status and various external factors).
After detailing the exception of California and New York being included in the list of places severely affected by opioid prescription abuse, it is pertinent to concentrate back on the prevalent form of the problem. It remains a fact that financially underprivileged eastern states continue to be at the top of the record of suffering areas. Malito and Fottrell's article contributes greatly to the justification of the phenomenon; it does, however, paint only the general picture of the issue. It does not introduce one to any individual case of a suffering person that would expose their feelings (towards their own struggle, as well as the opiate epidemic in a more broad sense), and maybe even provide examples of instances leading to the problem that the article failed to include. Focusing on a personal account of those directly involved is crucial to understanding not only the issue presented in the thesis, but should also be considered as the leading method in familiarising oneself with any given point of interest.
The 2013 documentary Oxyana allows one to be meet with the opportunity to do so.
Although the makers of the movie did not state it in any public statement, the viewer might assume that the year the film was released was not chosen coincidentally. Obviously, the general time of the release is consistent with the time of the opioid epidemic being treated as a widespread issue in the United States, but, more precisely, 2013 marks a spike in the abuse after its decrease in the prior few years (as depicted in the diagram presented in the previous chapter). Albeit it only a hypothesis, the production of the film might have been scheduled as such for a reason similar to the picture being analysed in this chapter – to help those interested in the issue (but also the people affected by it, as their involvement does not necessarily equal a full comprehension of the reason for the situation they found themselves in) understand its causes and ramifications more easily, while not omitting any significant facts that are seemingly too detailed or unaffiliated.
Even though the analysis itself is going to comprise of the first-hand experience of those affected, as stated earlier, their accounts might be occasionally supported by scientific data and other external piece of information. Such exercise is not by any means supposed to suggest that the individual struggle of the people presented in the film can only be considered valid if it has been officially recognised by external sources, but to yet again demonstrate that the mechanics of addiction are similar in both illegal substance and prescription abuse.
The official statement of Sean Dunne, the director of the film, lets the viewers familiarise themselves with the incentive that prompted the production, as well as allows for the anticipation of even more personal experience, as it corresponds with the victims' own accounts presented in the picture.
Taken from the official website for the film:

“It wasn’t long after I first set foot in Oceana, WV that I knew something wasn’t right. In fact, something was desperately wrong. This was one of the most beautiful places I had ever seen, filled with hands down the most honest and welcoming people I had ever met. Yet there it was, a constant and growing hum of anxiety. So we started to ask questions, and we started to get answers, all pointing towards a familiar narrative. Greed that led to overprescribing pharmaceuticals that led to addiction that led to poverty, lawlessness and hopelessness. Each story we’ve heard is more harrowing and haunting than the previous. Here is a place that represents our failures as a country, a microcosm of everything that’s gone wrong with the American Dream. Oxyana. These stories needed to be seen; they needed to be heard. Residents who were once talented, charismatic, hard working, God fearing, normal people have been reduced to nothing by the uncontrollable lure of this pill. There are high school girls with $800/day habits and families, who literally can’t provide food for their children, yet have full prescription bottles. There are former miners who have turned to dealing to make ends meet and pregnant women selling their bodies for another fix. It is a seemingly endless line of people who have lost the will to live.”

Obviously, the analysis will start at the very beginning – of the statement and of the film.
The action takes place in a relatively small town, Oceana. The viewer is probably not going to be surprised to discover that Oceana is situated in West Virginia, the state where the issue of opioid painkiller addiction has been proven to be the most prevalent and severe.
The title of the film, however, seems to be a word play on the name of the town. The place's “new” name comes from the drug OxyContin – which is another unsurprising fact when one takes into account the data presented earlier in the chapter (however, the director made opioid painkillers the main focus of his production, but the story touches on other types of abused medicines as well).
The film begins with various shots depicting Oceana – presented in an ominous, quiet, almost unsettling manner that one might interpret as a cinematic metaphor for the lethargic state opioids bring the user into. Overall, the film comprises of series of interviews given by the residents of the town that have been affected by prescription abuse (for easier differentiation, some of the interviewees will be given a fictional name, since their actual identities have not been revealed in the production); each one of them shares their exclusive experience, concentrating on a specific issue they struggle with the most.
The first interviewees, Patrick and Courtney, share their feelings towards Oceana as their hometown. Their account appears to be nothing short of positive – they praise the landscape, the long-lasting friendships, even the strong desire to keep coming back to the town, which, yet again, suggests the viewer the analogy of the early relationship between the user and the drug, when the former is usually still oblivious to the negative consequences of the still-developing habit.
According to Mayo Clinic's report on the development of opioid addiction:

“The length of time you use prescribed opioids also plays a role. Researchers have found that taking opioid medications for more than a few days increases your risk of long-term use, which increases your risk of addiction. The odds you'll still be on opioids a year after starting a short course increase after only five days on opioids.
A number of additional factors — genetic, psychological and environmental — play a role in addiction (...)”

Taking a habit that can sometimes last for years (as documented later in the film) into account, a few days might not seem to be a long period of time. However, the recreational effects of the medicine can easily be noticed during even a short-time treatment (especially in a first-time user that has not developed any kind of substance tolerance in the past), and the decision of continuing the use for non-medical purposes can clearly be made.
It is also worth mentioning that Patrick and Courtney's initial praise of Oceana as a place located in a beautiful natural environment which was once great and safe for raising children suggests a person's usual original perception of legally marketed medicines as not being harmful to the customer.
The next interviewee, Dominic, the local dentist, supports his neighbours' view of the town as something they are very attached to, at the same time realising that such mindset creates a sort of a contradiction, the existence of something an outsider would not suspect when experiencing the life in the town only superficially. He voices his concern:

“There's this darkness that has come over it, that has affected all those things in a way that it's even affected the natural beauty of this place, because as a person that lives here I almost can't look at it the same, because the people don't trust each other as they used to (…) there's more crime, the “us against them” mentality, and it's incredible, and amazing, and awful, all at the same time.”

The director then shows Courtney again (for future reference, she is the mother of another interviewee, Jason), who, referring to Dominic's statement, describes the beginnings of the epidemic in Oceana.
According to the woman, the town fallen victim to the phenomenon about fifteen years ago. She admits that at first she believed overprescribing the medicines was to blame, yet diminished the belief later, as even before the start of the epidemic, the use of cannabis and alcohol was prevalent in Oceana, but was noticeably less damaging than opioid abuse – therefore, she was not convinced that overuse of the medicines would be more risky than smoking or drinking. Some time later, however, she realised that the substances were considerably different from each other, and that the consequences of abusing prescription opioids were evidently more severe.
Business Insider (2016) provides a chart – a comparison of the level of addictiveness among chosen groups of substances – that validates Courtney's reflection:
 
All three components – pleasure, psychological dependence, and physical dependence – are marked as having the strongest properties when attributed to heroin, i.e. an opioid based substance. In comparison, the two other substances of interest, alcohol and tobacco, possess a lower risk of addiction, and, interestingly, a visibly smaller level of pleasure derived from the use. Such combination of factors seems to have contributed not only to heroin/opioids being placed at the top of the chart, but also to have explained what happened in Oceana.
Following Courtney's remark, the viewer is introduced to a twenty-three years old man, Aidan, who brings up his perspective concerning the lethality of prescription abuse in Oceana.
Aidan's age seems to have been mentioned purposefully. He remembers his expectations concerning high school – picturing it like the stereotypical American schools one can see in a film for teenagers and young adults – that, sadly, were not met at all. Instead, what he encountered was “kids would just slap the pills down your hand”. Now, few years after graduating, he tells the interviewer about the shock he experienced when he found out that numerous of his high school friends were already dead (which means they died before the age of twenty three) due to prescription opioid overdose.
His surprised reaction, while justified as a personal experience, involves a phenomenon that has already been unveiled and described by professionals.
As reported by Henry J Kaiser Family Foundation, the number of fatal opioid overdoses in West Virginia tends to be the highest among young adults (followed by people after the age of thirty-five up to forty-four).
The testimony and data presented above – as in several other cases described earlier – seems to be contradictory to the consensus or the generally held perception regarding the portrayed issue. Why would high school graduates, or even those who are still students, that most probably have already made plans for their future, be it academic or private, indulge in such destructive behaviour?
While the film does not directly answer the question – it does not describe the exact causes of the decision – it does in fact detail the palpable conditions that accompany the situation.
As stated by an Oceana native, Nikolai:

“When the prescription drug pill OxyContin hit the market the whole game changed. People started ripping each other off, they started breaking into people's homes, to fuel the addiction. That, to me, has been the biggest downfall of the area.”

Furthermore, the following account of two next interviewees, Vivienne and Isabel, supports Nikolai's statement by omnipresence (also among the young) of the problem, and touches on the root of it:

“It's an epidemic here. Anybody you could talk to here will tell you that they've at least dabbled in something [some prescription medicine]. They might not have gotten addicted to it, but they at least fooled around it. (…) Because there's nothing to do, this is such a small place, you look around, there's mountains everywhere. In big cities they've got movie theatres, and malls – we don't have anything like that to go and just do something.”

Although resorting to substance abuse as a result of boredom might seem reckless and worthy of contempt, especially in the age of easily accessible digital entertainment and means of communication whose use is almost effortless, it is not a rare occurrence.
Boredom, as understood by its traditional definition – lack of stimuli providing entertainment – does indeed play a role in developing addiction, however, to fully comprehend the issue, one should look for a broader interpretation of idleness.
Overwhelming routine – be it, as in the case of Oceana, plain, usually unenjoyable environment, or hours spent daily in a mundane workplace – can also create the feeling or emptiness and stagnation. Additionally, when worsened by the experience of abuse (of any kind and severity), the sense of boredom can evolve into the impression of being trapped, which, naturally, leads to the affected being tempted to employ whatever form of escape they are able to find, physical or, as in the situation in question, psychological.
In her piece for MedMark, Holly Holloway (2018) provides more details related to the connection of addiction and the provided, wider definition of boredom:

“Doing drugs or drinking can provide somewhat of a mental vacation from people’s current situation. When someone feels trapped and doesn’t know what to do with themselves, getting high or drinking can provide the same kind of mental stimulation as doing a fun  activity. Many of these people are also dealing with profound loneliness, anxiety, or are suffering from other situations that prevent them from being involved with hobbies or activities. People with anxiety and depression may feel that leaving their homes to engage in social activities is too stressful, and instead, prefer to stay home and numb themselves.”

Even though job-related routine was mentioned earlier as one of the reasons for developing addiction, lack of employment contributes to the issue as well (which might seem likely, if one associates unemployment with lack of sufficient physical activity or failing to pursue other areas of interest – such assumption might be, to a degree, correct, if individual cases are being taken into account, however, that is not what contributed to the development of the prescription addiction epidemic in Oceana.)
The city of Oceana, as one can derive from the film, used to be the place that profited mainly from coal mining. When, no longer than three decades ago, the industry in the area decreased in profitability, the problem of unemployment became evident, as most of the inhabitants were not trained in alternative employment fields.
Such kind of material hopelessness, as Erika – a single mother – and Stacy – pregnant at the time of the interview, as well as one of the earlier interviewees, Vivienne  – describe, lead to rapid increase of women that decided to become prostitutes (all three of them admit to having been involved in the practice).
Nonetheless, the additional income they received from prostitution, was not solely supposed to support the basic needs of the household. That was, as Vivienne describes, the time when the abuse of various other prescription medicines increased in Oceana. She describes the situation as a simple action-consequence equation: the inability to find employment fuelled depressive tendencies in inhabitants, who, consequently, turned to professional help. Yet, as mentioned earlier in the thesis, the people fell victim to drive-by appointments, where they did, in fact, receive the necessary prescription, but were not provided with sufficient guidance as to how to benefit from the medicines safely; therefore, the misuse of the drugs put the patients at the risk of developing dependence, which, in many instances, became the case.
This does not mean, obviously, that misuse of antidepressants and other non-opioid medicines did not exist in Oceana at the time when the coal mining industry was flourishing – the interviewees, however, try to paint the picture of what they themselves experienced. They did allocate their newly earned money to their and their families' needs, but the “needs” had become more than bills and food – they had to also include the obtained prescription. At the beginning, to improve their mental well-being, and later – to support the addiction (although, in the vast majority of cases, in order to produce desired effects, non-opioids were abused as simply an addition to opioids – not separately; this resulted in even bigger financial problems, as those struggling with dependence had to be able to purchase more medications).
In the interview, Vivienne relives her family's material striving:

“My dad is also addicted, me and him used together. [We] won the lottery, twelve thousand dollars (…) in one week it was gone, we had nothing left, we did 1080s [a reference to the dose of the abused medicine] every day. (…) I was scared, because... my husband, the reason he went to jail was because he was trying to support my pill habit, and I didn't have to do nothing, I sat at home all day, and he went out and robbed coal mines (…) so when he went to prison I had to step up and take that responsibility. (…) I sold one OxyContin for eighty dollars once and there were five people fighting over it. (…) I needed six to eight hundred dollars to actually get high. If I was lucky then I would actually get high daily.”

It is worth nothing that Vivienne mentions selling a single pill for a high price – such a black market for medicines also came to existence in Oceana. It was not often comprised of people like Vivienne, who decided to give up one need to satisfy another – instead, even those that were not affected by the epidemic directly, still participated and contributed to its escalation. By taking advantage of “drive-by appointments”, they would easily obtain the required prescription, to later illegally sell the medicine by highly inflated price.
Such activity, however, is not exclusive to places like Oceana, where the opioid epidemic has spread on such enormous scale – the data presented below, provided by United States Sentencing Commission (USSC), outlines the details of the felony, and further clarifies the reasons as to why it would eventually take place in Oceana.
USSC reveals that:

the majority of those convicted with illegal prescription opioid trade (as of 2018) were Caucasians (contributing to over fifty percent of the convicts); interestingly, the figure for black people was also considerably high: over thirty two percent (whereas Hispanics make up to slightly over ten percent of the convicted),
almost all of the convicts were American citizens (nearly ninety seven percent); USSC did not, however, disclose the nationality of the remaining three percent,
half of the convicted had no prior criminal records (a situation comparable to the position of the women in Oceana that had decided to get involved in prostitution, and then unlawfully sell some of their medicines); less than five percent of the convicts were disclosed as career offenders,
West Virginia was revealed to be the state with the third highest number of the people charged with the offence (nineteen convicts) – overtaken by Kentucky (twenty six) and Pennsylvania (thirty).

Additionally, almost seventy percent of the prison sentences related to the offence were shorter than five years; only thirteen percent of the prison sentences surpassed ten years of imprisonment.
One can yet again notice the pattern already discussed in the thesis several times. In this instance, however, Caucasians seem to contribute directly to the development of the epidemic (high number of convicts); similarly, the sole involvement of black people appears to be greater as the ones distributing the drug than those abusing it.
As presented before, the race of the addicted plays a significant role in distinguishing the opioid epidemic from other issues of said type. Whereas it is mainly considered as the factor contributing to the proneness to establish dependence, Oxyana presents the racial aspect as not only a cause of the problem, but also an obstacle in overcoming it.
In their interview, Joy and Victoria, a couple, describe how the negative stereotype associated with Caucasians and eastern states like West Virginia pertain to the issue of prescription opioid addiction being overlooked and downplayed by the general population of the US:

“If you had a quarter of addiction that we've been through, you would understand completely, you wouldn't even ask that question, you'd be like, damn, how are you still alive? (…) You know what? Nobody's going to care, you know, this is West Virginia, they think we're all much inbred pieces of shit. People are actually trying [to overcome the addiction], but you cannot get anywhere... It just sucks, man.”

Such approach to the issue – the diminishment and contempt preventing the victims from getting much needed help – together with other aspects contributing to the problem, yet again outside of the sufferers' control, (namely lack of proper medical care in their area of living) is likely to help one become more aware of the severity of it in terms of external factors being partially responsible for the victims' hardship.
It is vital to recognise that the word “partially”, pertaining to the fault of extrinsic factors contributing to the scale of the problem within certain individuals, was not used coincidentally. The thesis neither supports, nor suggests victim blaming, both as a general point of view, as well as in the question examined; nevertheless, in order to properly explain and understand the given subject, all aspects and sides of it need to be presented (especially when the direct account of those involved is available).
This specific point in question is being discussed in the film by yet another couple, James and Rena. After introducing himself, James provides the brief description of his current and past position:

“I have a problem, I have cancer, and I've been on drugs since I was twelve years old, but I've been on oxycodone since two thousand and seven. I have an addiction, plus I'm fighting cancer. So these are two fifteens [shows the drugs on the table], I'm ready to do one for me and one for my wife. This is how I do it [injects himself, then Rena, in the back of the palm].”

That short scene raises several points that ought to be detailed further, together with the main issue of personal responsibility.
James admits to have been involved in the consumption of drugs as early as in middle school. While such statement might appear shocking to the viewer, drug abuse in children is, in fact, an authentic phenomenon. An article from The Journal of the British Paediatric Association, Drug Abuse In Children And Adolescents, published in 1992 (which is probably the approximate time of James' childhood), provides the figures and specific elements for the abuse in the US:

“National American surveys usually report higher rates [as compared to Great Britain]. Most dramatic in the USA is the increase in cocaine use: in 1985, over 1,1 million 12-17 year old adolescents had tried cocaine. (...) Overall about 5% of adolescent drug abusers in the USA meet the criteria for 'dependency', with multiple drug abuse being the rule rather than the exception. The age at which adolescents start drug taking is getting lower: an average of 13-15 years. Girls are less likely to use drugs and start later than boys. (...) Earlier illicit drug abuse is often associated with heavier subsequent drug abuse, more persistent abuse, and the abuse of 'harder' drugs.” (p. 1245)

The reader should pay special attention to the mentioned proneness for continued and/or aggravated drug abuse later in life – the fact most probably played a significant role (among other factors) in James falling victim to the opioid epidemic several years later.
Another, probably less surprising, point raised by the interviewee is him struggling with cancer; he does not state it directly, however, taking into account the sole nature of the issue – addiction to prescribed opioids – as well as the condition of medical facilities and care in certain areas, it can be safely assumed that the painkillers James had been prescribed to alleviate the pain related to his illness, were responsible for him developing addiction.
Finally, what the viewer might find unusual, is the method of consuming the drug. In most cases, commonly used prescription painkillers are to be taken orally; obviously, there are certain cases and doses of the medicines that are to be injected, but the injection is usually done by a nurse or another medical professional legally allowed to perform injections (which, in case of opioid painkillers, are muscle injections; James injecting palm suggests that he aims to insert the substance directly into the vein).
The film does also depict one of further interviewees preparing the injection – his method is identical to that of assembling the form of illegal drugs, most notably diacetylmorphine (heroin), that is ready to consume. One can conclude that the director's decision to film the process was supposed to draw similarities between prescription opioids and illicit substances of said type.
But what does James' story include, that would indicate at least a part of the responsibility of developing addiction lies with the person affected? The question seems to be answered by Rena.
The woman shares her experience with lack of self-confidence and being self-conscious of her physical appearance as a teenager. She admits that said struggles contributed to her decision to try self-harming as a method of relieving the mental anguish; as the results of physical pain resulting from the self-inflicted injuries, she was prescribed opioid painkillers. Soon after she began the treatment, she claims to have realised that whereas the medicine did manage to alleviate the bodily discomfort, the side effects – the reason why prescription opioids are used recreationally – provided her with psychological ease much stronger than the one she was able to achieve through self-harming.
Rena also asserts that the prescription abuse – more specifically, the financial struggle that it caused – started the chain of events that lead to her meeting James, her current husband, whom, she claims, helped her finally overcome the self-confidence issues instead of simply temporarily suppressing them with medicine abuse. She did not, however, stop the misuse of OxyContin, and they both have no intention of doing so in the near future. Rena even calls the substance their “love drug”, as she believes that not only did it guide her to encountering James, but also is one of the reasons they still deeply love each other (James agrees with the statement).
Rena's story does in fact provide an example of misusing prescription medicines, and, as a consequence, becoming addicted to them as a result of choosing the misuse as a means of overcoming a problem that concerns a specific individual and/or that could be resolved by other ways of treatment, designed specifically to settling it. Certainly, one could argue that “drive-by appointments” are most probably an issue present in mental health facilities as well, so that even if Rena willed to turn to a professional that would help her accept and admire her physical appearance, the treatment she would have received would not be sufficient, or would even lead to the worsening of the problem. While the point of “drive-by appointments” affecting the quality of the services provided by therapists are satisfactory, the viewer is not introduced to the basis of the woman's decision to start her own “treatment” - while it might have been fuelled by the unavailability of professional help, it might have as well be built upon her own choice not to try any suggested approach.
Furthermore, what also supports the theory of personal responsibility, is the notice of OxyContin being one of the foundations of the couple's successful relationship – a scenario that is rather absurd.
The differentiation between opioid addiction caused by both external and internal (personal) factors was necessary to characterise the issue in greater detail, depicting its vast extent and obstacles in overcoming it caused by the need to find various solutions, suitable for diversified cases.
Both aspects lead to a similar outcome – addiction – that might be discerned by the level of severity associated with surmounting the dependence; the problem itself, however, can result in a condition closely related to, especially psychological, dependence, that should not be omitted when trying to fully understand the dilemma.
According to MedicineNet, substance withdrawal can be defined as:

“Abnormal physical or psychological features that follow the abrupt discontinuation of a drug that has the capability of producing physical dependence.”

Withdrawal occurs in all kinds of abused substances, and thus might vary in severity, length, and symptoms. In case of opioids (both prescription painkillers, and illegal kinds), sudden cease to consume the required item is likely to cause (following Treatment 4 Addiction, An American Addiction Centers Resource)

excessive sweating, independent of the external conditions, occurring usually during the night,
other physical manifestations of withdrawal, namely muscle pain, flu-like symptoms, nausea, diarrhoea, and cramping in lower abdomen,
psychological discomfort – increased anxiety, agitation, insomnia, as well as inability to concentrate.

The aforementioned conditions are of highest intensity during the first five days after stopping the consumption of the substance; next, the individual's body and brain start adapting to function properly without the required intake of the drug.
Nonetheless, there are medicines supposed to nullify the symptoms, and help the addict fight the urge to alleviate physical and mental discomfort by relapsing on opioids. Interestingly, the medicine used in the treatment, Subtex (and several other of its brands), consists mainly of another opioid, buprenorphine; that specific extract of papaver somniferum, while matching the definition for an opioid, does not produce the effects desired to be acquired from recreational use. Such quality allows the body to register the needed dose of opioid, with the individual being unable to achieve any previously seeked reaction, thus allowing the withdrawal period to pass almost unnoticeably (the effectiveness of the treatment varies due to the dose of the opioid the patient was used to receiving).
Naturally, as with any other treatment, no success is guaranteed, since each individual's physical and mental properties might affect the quality of the process. Whereas in most cases the disturbance of the therapy of the discussed condition will lead to temporary noticeable uneasiness and pain, there is a risk of a patient (either subjected to treatment or not) not only being immune to the provided remedy, but also establishing a syndrome including symptoms of severity much greater than those present in classic opioid withdrawal.
In rare cases, the sudden cease of opioid intake might lead to withdrawal-induced psychosis, a state which, in general, can be defined as:

“a loss of contact with reality, usually including false beliefs about what is taking place or who one is and seeing, and hearing things that are not there.”

Psychosis induced by opioids, according to Treatment 4 Addiction, usually manifests with severity greater than the same state induced by other drugs with sedative properties:

“Opiate withdrawal induced psychosis is very different (...). It derives from a place of mental instability and severe anxiety. A sense of hopelessness is very common when in a withdrawal induced psychosis. Judgment and logical thinking are not present during a state of psychosis and can lead to impulsive actions. Depending on the circumstances and possible pre-disposed mental illnesses, a state of psychosis, especially in withdraw, can be extremely dangerous. (...) It is this desperation and hopelessness that will cause an addict to make decisions that may go against their morals or values. (...) This can be very dangerous. Someone in a state of psychosis is extremely unpredictable. Addicts in opiate withdrawal induced psychosis will go to any length to get what they desire.”

Such description – especially regarding making impulsive and hazardous decisions – matches the confession of one of the interviewees, Kurt.
The man describes himself as being in his mid-thirties, and addicted to opioid painkillers (he even shows the drug packages, detailing the doses of the medicine each of them contains, and how much they cost), as well as to unspecified antidepressants.
Before beginning to tell his story, he – similarly to James – injects himself in the back of his palm with a dose of medicines (a painkiller mixed with antidepressants). The viewer might notice that, despite the period of time that has passed since the injection, Kurt does not show any signs of drowsiness, or other symptoms of being under the influence of the substances he has taken. This might suggest that the purpose of the dose in question was to simply avoid the discomfort of withdrawal, not to satisfy the need for the desired effect.
Kurt describes his teenage years in Oceana; the man has never moved out of the town. He used to live with his parents and younger brother, Eric. Both his mother and father were addicted to illegal opioids, which they later replaced with prescription painkillers. His father was also an alcoholic.
In spite of his parents' addiction, the family life was fairly undisturbed by the condition. However, one night, probably as a consequence of a lack of professional help, Kurt's father suffered psychosis caused by untreated withdrawal. The interviewee was not at home that particular night, and, as he now confesses, because of what he discovered after having been back, he believes it was only because of God's providence.
Kurt's father body was scattered on the kitchen floor, next to an empty bottle of an opioid painkiller, and a pistol; his head had a noticeable gunshot wound. The body of the mother was in her bed, dressed in pyjamas – Kurt claims that she was murdered in her sleep. Finally, he found Eric, also dead, lying next to his bed; the body expressed the signs of struggle or defence.
The police concluded that the father, paranoid and desperate to find the drug he needed, found out earlier that his younger son, who had started to grow concern over the parents' dependence, hid the painkillers under his bed. After refusing to give the medicines back to the father, Eric was shot by his father. Next, the man went to the bedroom he shared with his wife, realised she was not woken up by the gunshot, and also murdered her. Eventually, he consumed the medicine he forcefully took from his son, and committed suicide shortly after.
The tragic story of Kurt's family, in its atrociousness, might appear to be an exception, or a part of the very low percentage of extreme cases of prescription abuse. While, according to Bureau of Justice Statistics (BJS), the crimes related to substance abuse (both legal and illegal) in the USA make up only about eighteen percent of all offences, like any other issue, it should not be neglected.
A adduction of a case from outside Oceana might help one realise the severity and omnipresence of this seemingly minor phenomenon.
The city of Mishawaka, Indiana (interestingly, it was not put on the list of the states that are most affected by the opioid epidemic; a proof of the ubiquity of the problem), is one of the places that experienced the issue. An article by Megan Thielking (2017) for Stat News, A Doctor’s Murder Over An Opioid Prescription Leaves An Indiana City With No Easy Answers, quotes the harrowing story of Dr Todd Graham.

“Dr. Todd Graham wasn’t yet halfway through his workday at South Bend Orthopaedics when a new patient came into his office here complaining of chronic pain. Heeding the many warnings of health officials, he told her opioids weren’t the appropriate treatment. But she was accompanied by her husband, who insisted on a prescription. Graham held his ground. The husband grew irate. The argument escalated to the point that Graham pulled out his phone and started recording audio until the couple left. Two hours later, the husband would return, armed. (...) the incident wasn’t out of the ordinary - physicians here and across the country have grown increasingly accustomed to disputes over opioids. (...) Two hours after their verbal scuffle in the orthopaedics office, Michael Jarvis - who had wanted that prescription so badly - had come after him again, this time in the parking lot. Again, Jarvis shouted. He ordered two people at a nearby picnic table to leave. Then he pulled out a semiautomatic weapon and shot the doctor who wouldn’t give his wife pain pills.”

The case quoted above demonstrates even more hazardous side of severe opioid addiction. While the author does not state whether the man who threatened doctor Graham was in the midst of withdrawal, and, consequentially, psychosis, the reader should acknowledge that the prescription Jarvis was demanding was not intended for him, but for his wife. This fact generates several questions – was the culprit lying, as he was convinced the doctor would have been more likely to prescribe the desired medicine for his wife? If so, what was his reason for believing so? Was his mere presence during the appointment supposed to intimidate the doctor and pressure him into providing the prescription? Or was Jarvis addicted to illicit opiates that were not available for him at the moment, and tried to take advantage of the fact that his wife's condition required medical attention? Had he hurt or abused her particularly for this reason?
In the article, the reader will not find the answer for any of the cited questions, which, in fact, makes the specific case – and the whole issue of painkiller addiction and withdrawal – even more horrifying. Each scenario could possibly be true, and, taking into consideration the scale of the epidemic, it can be assumed that that all of the aforementioned probabilities have took place in other cases that did not receive any or enough media attention.
What is more, Doctor Graham's example encourages one to recognise that not only those in close vicinity of the sufferer of psychosis are in immediate danger. The doctor was not in any way related to the murderer, and met his tragic fate only because of trying to properly execute the medical practice by not providing the patient with treatment that would be improper or even harmful for her. Yet again, the scenario establishes another possible one – what if Jarvis learnt about a person, not necessarily associated with medicine, that was currently in possession of an opioid painkiller, and decided to threaten them instead? Such possibility appears even more random, but definitely not absurd, and thus, more alarming.
To support the concept of the jeopardy a third party can be put in because of opioid prescription addiction, Thileking refers to the figures associated with physical and verbal attacks aimed at individuals in their workplace, with the focus on patient-on-doctor violence:

“Health care workers face a disproportionate share of violence in the workplace: An average of 146 attacks for every 10,000 workers, compared to seven assaults per 10,000 workers across the entire U.S. labour force.”

She also mentions the dilemma physicians are often met with when trying to execute the proper treatment:

“First-time patients [such as Jarvis' wife] who are seeking painkillers present a tricky problem for doctors who say they often need considerable time to diagnose what’s wrong with the patient and figure out how best to help. If a patient demands the quick fix of an opioid prescription instead, the situation can swiftly escalate. But doctors say they’re not sure what to do when that happens. They often don’t want to call the police on a patient. Yet they don’t want to give in and write an unnecessary prescription, either.”

Presumably, such puzzling situation doctors are likely to find themselves in, might be the factor that discourages those interested from pursuing a career in medicine; ergo, causing the lack of physicians (“drive-by appointments”) not only in the areas that are affected by the opioid epidemic the most, but also creating the problem in seemingly unaffected areas of The United States.
In order to conclude the analysis of the film in a coherent and logical way, it is best to yet again touch on what commenced it – a statement from the director. This time, Sean Dunne, in an interview with Nick Dawson (2013), rightfully pays respect to those that participated in the production, and, at the same time, restates what has already been aforementioned in the chapter, regarding the cases of the people that might have not been the victims of the phenomenon themselves – how the opioid epidemic affected him both personally and by proxy:

“Certain people were aware of us before we got there and wanted to have their voices heard. Others took a bit more time to warm up to us. But once we got going and got a few interviews under our belt the tide started to shift in our favour, word spread that what we were doing was legit and people began to embrace us. Once our cameras were rolling I couldn’t believe how candid everyone was. We treated them with respect and they did the same in return. (…) The Oxycontin epidemic was somewhat on my radar from personal experiences, but I wasn’t really aware of the full extent of the situation in West Virginia until we went there and saw it firsthand. (...) Obviously when you’re infiltrating and documenting a subject as sensitive as this you are going to be met with some resistance. We had some threats of violence that were very real and extremely nerve wrecking; we even had two death threats. In a town as small as Oceana there is really nowhere to hide, especially with a film crew, so we had to face that stuff head on.”

Later in the interview, Dunne remembers how difficult the process of editing the film was for him and the rest of the filming crew due to the affecting and tragic subject matter, but, in addition to that, he mentions that he is happy for introducing the issue to a large audience.
As the main representative of the problem, included in the present chapter, Oxyana helps the reader in a way infiltrate, as the director himself has mentioned, the psyche and sensitivity of those that were personally involved in prescription opioid abuse, whether by choice, or by the affection of unfortunate circumstances. It rehashes the data presented at the beginning of the chapter – the effects opioids have on the user, their similarity to illegal drugs of the same kind, as well as the problems related solely to the situation a given area struggles with due to the lack of sufficient professional help – and also introduces one to entirely new elements the epidemic, namely the cost of the addiction (financial, as well as health-wise) in an individual, and the black marked of reselling the medicines in question, and means of making money.
In general, the aim of the chapter was to detail the widespread and highly lethal, albeit usually underdiscussed, issue of prescription opioid abuse, by focusing on the most affected demographics and the interesting factors contributing to the people in question falling victim to the epidemic. The presented data has been supported by introducing official statistics that – although most probably not as powerful and emotion-inducing as the direct testimonies provided by Oxyana – prove the unambiguous, yet seemingly contradictory, connection between trying to treat the pain without the adequate supervision and care of a professional, but also with the abundance of physicians to choose from – with developing opioid addiction, the consequences of which are not only detrimental to physical health, but also to the victim's mental condition.

5 September 2020

The History Of Drug Use

The usage of drugs and widely understood psychoactive substances have been known as long as humanity's recorded history lets us discover.
According to professor Elisa Guerra-Doce, people have tried to alter their consciousness ever since prehistoric times:

"(...) the evidence shows that people have been chewing the leaves of a plant called the betel since at least 2660 B.C (...) The plant contains chemicals that have stimulant- and euphoria-inducing properties, and these days is mostly consumed in Asia.
The earliest evidence of opium poppy use in Europe comes from the Neolithic site of La Marmotta in Italy, which dates back to the mid-sixth millennium B.C., according to the study. The domestication of the plant in Europe likely began around that time, in the western Mediterranean, and then spread  to northwestern Europe by the end of that millennium." (Guerra-Doce, 2015)

In the cited fragment, the author mentions two plants – the betel, and the opium poppy – both of which might be familiar to the reader (however, as also stated in text, the western readers might be more acquainted with the latter), since their usage is still prevalent today. It is important to note that, nevertheless, there was no sudden revival of the usage of certain substances, but they were the subject of a custom thorough the time leading to the present day. The author of the official website of The International Network of People who Use Drugs presents the timeline of drug usage – including mainly opium, as well as various stimulants, but also mentioning widely consumed and , in most cases, legal products, that contain an addictive component, like coffee, tea, and alcohol  – starting from the habits of the ancient Sumerians, up to the year 2014.
The report asserts that the beginning of opium usage outside of Europe ought to be placed in the year 5000 B.C., since the presence of a certain ideogram in the Sumerian writing system. However, there seems to be no trace recorded of any other drug thorough the next 1500 years – both in Europe and other parts of the world – when the first known use of alcohol is acknowledged in Egypt, and when the practice of drinking tea starts in China (which is also characteristic for the region even today). Aside from what can be learnt from Guerra-Doce, opium is tracked in the Old Continent yet again in present-day Switzerland, where it appeared in the form of edible seeds.
Interestingly (especially for the further part of the chapter), alongside with the description of drug use, the author also mentions the first ever attempt at substance prohibition. The Endeavour took the form of a religious teaching, which was conducted by an Egyptian priest, who forbade his listeners from visiting taverns, explaining that drinking alcohol would make them behave “degraded like beasts”.
The article then temporarily abandons strictly historical records, and, instead, focuses on the mentions of addictive substances in the Bible (which, obviously, influenced the behavior and attitude of its readers); the cited part (Proverbs, 31:6-7) encourages those who witness someone suffering to offer them alcohol, which will supposedly help the offered forget their hardships.The reference to Christianity also introduces the part of the report that concentrates on the A.D., with the words of the Bishop of Constantinople, St. John Chrysostom: “I hear man cry, ‘Would there be no wine! O folly! O madness!’”After that we learn about the start of the use of yet another popular substance, tobacco, in Europe – the drug was imported to his homeland in 1493 by Christopher Columbus, who encountered its usage during one of his voyages.
What is common for all the aforementioned records is that the use of the substances was purely recreational (with the possible exception of alcohol being the cure for misery – still, it cannot be considered an appropriate medical remedy). Outlining the beginning of the 16th century, however, the author brings up the Swiss alchemist, Paracelsus, who was the first to propose opium as a means that can be used in medicine (which, on the other hand, is essential for latter chapters); yet, the acclaimed researcher specified neither the particular branch of medicine papaversomniferum (the scientific name of poppy plant) could be applicable for, nor the particular issue opium could be a cure for. It is possible that in the light of seemingly positive effects it had on the users' mental state (albeit only temporarily), Paracelsus suspected the properties of opium could be somehow introduced into the methods of an actual therapy.
After describing several other attempts at prohibition (namely by czar Michael Fedorovich and Sultan Murad IV; focusing mainly on tobacco, both the user and the supplier were to be tortured or executed), the above-mentioned ambiguity is cleared by pointing out the statement of the English physician, Thomas Sydenham, who attributes unprecedented and exceptional painkilling properties to opium: “Among the remedies which it has pleased the Almighty God to give to man to relieve his sufferings, none is so universal and efficacious as opium.”
En passant, a worth mentioning and thought-provoking employment of consciousness-altering substances can be found in the 18th century England: only those who “would take oaths of allegiance and of belief in the King’s supremacy over the Church” could be allowed to consume alcohol legally. This exception from prohibition is a clear example of a benefit offered in exchange for political gain.
With the passage of time, however, the attitude towards certain addictives began to change, according to the author. Shortly after the first known inclusion of drugs in politics, at the other side of the Atlantic Ocean, in Connecticut, the first temperance group started, focusing principally on alcohol addiction and abuse.
Accordingly, in their book Drugs in American Society: An Encyclopedia of History, Politics, Culture, Nancy E. Marion and Willard M. Oliver (2014) described alcohol usage as:

"(…) a disease, produced by a remote cause, and giving birth to actions and movements in the living body that disorder the functions of health. The habit of drunkenness is a disease of the mind." (p. 54)

Likewise, looking to the East, in 1792 Chinese rulers passed the law that prohibited the usage of opium, under threat of capital punishment.
Nevertheless, the growing animosity towards drugs (at the time mainly alcohol and opium) did not prevent the emergence of different substances. Near the end of the 18th century, cannabis – another well-known (as well as controversial, due to varying restrictions around the world) modern drug – arrived to France as a consequence of Napoleon Bonaparte's return from Egypt, where it had already been in use.
Few years later, at the beginning of the 19th century, opium became the center of attention in the world of medicine yet again, as a derivative of the drug, morphine was isolated in Germany. FriederichSerturner, who conducted the procedure, first tested the effects of morphine on dogs, describing it as a “sleep-inducing molecule” (which came to him as no surprise, since the sedative impact of opium on the organism). Later, after risking self-medication with his discovery that, ultimately, brought him relief and left no negative side effects, he began to test continuously morphine on volunteers, including himself. Finally, he was able to determine an efficient, yet safe oral dose (as medical syringes had yet to be devised by the time of Serturner's discovery), and, in the same decade, he opened a pharmacy in northwestern Germany.
Despite earlier claims and research on the painkilling effects of poppy plant, FriederichSerturner's work marks the official introduction of an opium-related medication to the market. Interestingly, morphine was advertised not only as a pain reliever, but as a medicine with various other qualities (some of the qualifying as meeting the criteria of recreational use), such as documented by Chandrasekhar Krishnamurti and Chakra Rao (2016):

"(...) anxiolysis, euphoria and feelings of relaxation. (...) The drug is also dramatically effective in cardiogenic pulmonary oedema as it calms the patient and reduces dyspnoea and myocardial oxygen demand."

At that time, addictive purposes of opium were not widely discussed, or even known. In 1822, Thomas De Quincey, whose signature work, Confessions of an English Opium Eater, is believed to have introduced the topic of drug dependency into popular literature, wrote:

"Making allowance for constitutional differences, I should say that *in less that 120 days* no habit of opium-eating could be formed strong enough to call for any extraordinary self-conquest in renouncing it, even suddenly renouncing it. On Saturday you are an opium eater, on Sunday no longer such." (p. 34)

Taking the drug's apparent non-addictiveness and medical versality, the demand for papaversomniferum, had siginifically increased since the discovery of morphine. In 1839 however, the export of opium from China (the main supplier) to Europe through British East Indian Company, was at the risk of being halted entirely, as the Daoguang Emperor, concerned about the rising number of opium-related problems (mainly the issue of addiction that increased after the EIC started to illegally grow the plant in India – in contrast to Western societies and governments, Chinese rulers had not only been interested in the positive properties of the drug, but also were not oblivious to its disadvantages and tried to warm the citizens about them), did not agree to legalize the culture of the plant, and tried to stop the trade.
When the Emperor's diplomatic attempts at abolishing the sale failed, the General Governor of Hubei and Hunan provinces ordered to forcefully impound all opium from the western sellers' shops, and ordered the incoming ships to give up their cargo.
This measure resulted in the British deploying their military to China (thus starting the war), and ultimately, defeating the much more numerous Chinese forces. The First Opium War resulted in the Treaty of Nanking being signed; the document allowed free trade with Western merchants, as well as ordained the opening of five new ports.
The unrest related to opium did not decrease the interest in the manufacturing and distribution of other substances in the West, mainly thanks to the popular figures involved in the process. Abraham Lincoln mentions his doubts related to the temperance movement in his Temperance Address from 1842:

“In my judgment, such of us as have never fallen victims, have been spared more from the absence of appetite, than from any mental or moral superiority over those who have. Indeed, I believe, if we take habitual drunkards as a class, their heads and their hearts will bear an advantageous comparison with those of any other class. The demon of intemperance ever seems to have delighted in sucking the blood of genius and of generosity. What one of us but can call to mind some dear relative, more promising in youth than all his fellows, who has fallen a sacrifice to his rapacity?” (p. 272)

Nevertheless, despite such assessment from the president, the Temperance movement was still active. Three years later after Lincoln's speech, the State of New York delegalised public sale of liquor. The ban, nonetheless, lasted only two years before being overturned in 1847.
The attempts at restricting the sale and consumption of alcohol might have been unsuccessful at the time, but the foundation of The American Pharmaceutical Association at the beginning of the new decade seemed to have established – albeit not as strict – but a similar goal in association with pharmaceuticals (1958):

“(...) to aid in the detection of prevention of adulteration and misbranding or drugs and medicines (…) To support a system of of licensure and registration of pharmacists which will assure to the public the the availability of competent personnel to discharge the accepted functions of the practice of pharmacy and assure the availability of pharmacists and pharmaceutical service which will provide at all times for the distribution of drugs and medicines under the supervision of qualified pharmacists.” (p. 4)

Similarly, education and supervision became the main purpose of action of the Temperance movement, as well as other parties concerned with the problem of substance dependence (in the wake of such shift in the methods of preventing addictions, The Personal Liberty League of the United States was created). By the year 1900, all states have been subjected to laws introducing “temperance education” as a part of school curriculum.
It is worth noticing that the establishment of  The Personal Liberty League of the United States did not prevent the exclusion of certain people from being subjected to forceful abolition. Henry Cabot Lodge, a senator from Massachusetts, proposed a bill that did not allow the sale of liquor and opium to “aboriginal tribes and uncivilized races (…) uncivilized elements in America itself and in its territories, such as Indians, Alaskans, the inhabitants of Hawaii, railroad workers, and immigrants at ports of entry”.  
The beginning of the new century was marked by the growing suspicion of opium and its derivates (but also a fairly new invention and a stimulant, cocaine) for not being only a miraculous cure for pain. In 1905, Senator Henry W. Blair concluded:

“The temperance movement must include all poisonous substances which create unnatural appetite, and international prohibition is the goal.”

The skepticism resulted in the establishing of Pure Food and Drug Act – the sale of any derivative of opium was banned until the product was labeled as containing such substances. (Around the same time, Coca-Cola removed cocaine as one of the ingredients, and replaced it with caffeine).
Soon, the concern was not only limited to politicians, but also spreaded among general population. Dr. Charles B. Towns (1914) wrote in his article in the Century Magazine, pointing at analogous properties of tobacco, alcohol, and opium:

“A boy always starts smoking before he starts drinking. If he is disposed to drink, that disposition will be increased by smoking, because the action of tobacco makes it normal for him to feel the need of stimulation. He is likely to go to alcohol to soothe the muscular unrest, to blunt the irritation he has received from tobacco. From alcohol he goes to morphine for the same reason. The nervous condition due to excessive drinking is allayed by morphine, just as the nervous condition due to excessive smoking is allayed by alcohol(...) Morphine is the legitimate consequence of alcohol, and alcohol is the legitimate consequence of tobacco. Cigarettes, drink, opium, is the logical and regular series.”

Finally, in 1914, with the introduction of The Harrison Narcotics Tax Act, the sale of opiates and products containing cocaine was strictly regulated (although, the latter could still be distributed under certain conditions). The Act omitted marijuana, a substance that grew in popularity, mainly due to this sole reason.
This changed in 1937 with the enacting of The Marijuana Tax Act. Commissioner Harry J. Anslinger noticed:

“How many murders, suicides, robberies, criminal assaults, hold-ups, burglaries, and deeds of maniacal insanity it [marijuana] causes each year, especially among the young, can only be conjectured.”

As with any of the aforementioned cases of banning or restricting the use of addictive substances, the 1937 act received  vocal criticism. In The Marijuana Bugaboo, colonel J.M. Phalen asserted that the effects of the usage of cannabis are no more harmful than the effects of smoking cigarettes. He also maintained that there would not be any persecution of soldiers (the article was published in 1943) using the drug as he did not consider it a problem of any kind.
The negative effects of widely known addictives – especially alcohol – began to be recognised more often, and became more available to the population, mainly thanks to the popular figures involved in the process.
However, when it comes to mainstream consciousness, drugs became popularised in the 1960s, as their usage, together with colorful clothes, flower-painted vans, and music festivals was one of the characteristics of the “age of love”, the peak popularity of hippy subculture. As stated in Drug Enforcement Administration, A Tradition of Excellence (2009):

“In 1973, President Richard Nixon declared “an all-out global war on the drug menace” and sent Reorganization Plan No. 2 to Congress. “Right now,” he pointed out, “the federal government  is fighting the war on drug abuse under a distinct handicap, for its efforts are those of a loosely confederated alliance facing a resourceful, elusive, worldwide enemy. Certainly, the cold-blooded underworld networks that funnel narcotics from suppliers all over the world are no respecters of the bureaucratic dividing lines that now complicate our anti-drug efforts.” (p. 13)

Richard Nixon also requested establishing a federal agency that would integrate the government’s politics concerning prevention of drug abuse and trafficking; the proposal provided the basis for the creation of DEA (United States Drug Enforcement Administration). DEA would take over the drug enforcement operations of the consequently destabilished Bureau of Narcotics and Dangerous Drugs.
The Senate referred to the Federal Bureau of Investigation's broadened role in the field (DEA would be permitted to use the data FBI has obtained on drug-related crimes), coordinating the extortions of various local and foreign organs specialising in working against narcotic (as well as citing the assets of general administration, inter alia, diminished susceptibility for corruption and abuse of power), and determining the creation of the DEA as the catalyst for the mutual efforts of all other forces to be condensed together in order for the to result in a more successful outcome as the main benefits of the creation of the new agency.
One of the crucial factors in carrying out fruitful operations was efficient and trusted intelligence. The author describes the need:

"Accurate and up-to-date information was required to assess the operations and vulnerabilities of criminal networks, to interdict drugs in a systematic way, to forecast new methods of trafficking, to evaluate the impact of previous activities, and to establish long-range drug strategies and policies. Included in the DEA mission was a mandate for drug intelligence."

The mandate was passed and at the beginning of July 1973 the DEA established its own Office of Intelligence. Similarly to the base for creating the entity itself, the benefits of the coordinated efforts of non-federal agencies was quoted as one of the biggest advantages of the the newly-established office, together with identifying the past mistakes and insufficiencies in drug enforcement.
The office comprised of three main branches of interest: operational (analysis of the obtained data), tactical (finding and identifying drug traffickers), and strategic (recognising a general pattern according to which traffickers and producers operate).
Interestingly, shortly after the creation of the Office, the majority of those in charge of its operations did not have any experience in working in such field. According to the author, less than fifteen officials had worked as intelligence agents before. Such situation, however, did not prevent the DEA from creating its first task force - still in 1973. The UID (Unified Intelligence Division) and its achievements have been characterised by the author as:

"This pioneering role expanded the horizons of drug law enforcement field intelligence units, which, at the time, were often limited to collecting information, maintaining dossiers, and providing limited case support. This proactive stance was immediately successful as UID was able to develop and disseminate extensive intelligence on traditional organized crime-related drug traffickers and identify not only the leaders, but also those who were likely to become leaders."

The compelling activities of the division carried out through the next decade; the operations of the UID were the main factor in the decrease of cocaine abuse on the East Coast.
Despite the success of the UID, the DEA had to also focus on other factors that would provide a fruitful fight against drugs - one of them being proper organization of the tasks and procedures. The role was appointed to the DECS (The Drug Enforcement Coordinating System). The system monitored all the activities and cases the DEA was currently working on - a measure that prevented different agencies from unnecessarily repeating their efforts, but, most importantly, the DECS ensured the safety of the agents and various other officials, who thus could be informed of the difficulty level of a certain case and, subsequently, of any jeopardy connected to it.
An office similar to DECS, NADDIS (National Narcotics Intelligence System) was also developed the year the DEA started; it was of great importance and interest, however, as it was the first index of the operations that involved minimum of manual effort, being highly computerised instead. The author concludes its formation as:

"(...) possible because the DEA was the first law enforcement agency in the
nation to adopt an all-electronic, centralized, computer database for its records. NADDIS, composed of data from DEA investigative reports and teletypes, provided agents in all DEA domestic offices with electronic access to investigative file data."

"Investigative data" referred not only to illegal manufacturers and traffickers, but also to the victims of drugs abuse. The aim of DAWN (Drug Abuse Warning Network) was to monitor the scale of the consumption of illegal substances in the United States. DAWN, nevertheless, did not rely only on sources connected to the DEA; the Network joined efforts with hospitals, tracking the admissions of the patients that suffered with the use of illegal drugs or used legal substances recreationally. The author provides a descriptions of the clinics involved in operations conducted by DAWN:

"Non-federal, short-stay general hospitals that feature a 24-hour emergency department (...) The data from this sample were used to generate estimates of the total number of emergency department drug episodes and drug mentions in all such hospitals."

The focus on short-stay hospitals appears to be important, as drug-related cases generally require immediate intervention, but a long-term stay after the treatment is, in most cases, needed.
The investigation of hospitals was supposedly linked to passing Narcotic Addict Treatment Act. The aim of the act was to identify and list the doctors (but also nurses) who admitted narcotics to their patients suffering with drug addiction as a treatment. As stated by the author, the act "eliminated the indiscriminate prescription
of narcotics to addicts and reduced the diversion of pharmaceutical narcotics."
When describing the versality of the DEA, it is important to yet again acknowledge one of the core reasons for its development - the diversity of resources, which, as a consequence, leads to the Department's functionality and high adaptability to disparate environments.
A year before President Nixon's declaration, the amount of heroin illegally trafficked from Mexico reached a record number (it surpassed the amount of the drug coming from Europe by forty percent). As the control of the trafficking was no longer manageable by the forces that usually operated at the southern border, the Mexican government asked The United States for cooperation. The request resulted in three separate applications of drug enforcement - Operation Special Enforcement Activity in Mexico, concentrated in Sinaloa and focusing on heroin and opium, Operation Endrun - in Guerrero, targeting marijuana trafficking, and Operation Trident (suspending the movement of other illicit substances).
The fight against drugs, however, was not limited to more “casual” forms of actions, like the aforementioned intelligence or dealing with border traffickers. The DEA yet again took advantage of the still fairly new tools that, thanks to their computerisation, proved to be very useful to their mission.
Due to the fact that video cameras in the seventies were much bigger and heavier than their today's equivalents, the agents used mainly sound recorders. The equipment, however still heavy and relying on batteries that often turned out to be of short durability, was concealed as a belt worn by the person underneath their clothes; still, this method could only be used it the member of the DEA was able to be physically present at the scene. If the situation required higher level of concealiblity, the so called “pen registers” were relied on. The author describes such interesting in a greater detail:

“Pen registers, or dialed number recorders, were more advanced than the older versions, which actually punched holes in a tape, similar to an old ticker tape, in response to the pulses from a rotary dialed phone.“

The then-available technology did not only help in obtaining evidence, but also made the communication between the staff (and, obviously, between the agents assigned to a certain mission) easier. No mobile phones were used at the time being (with an exception of a specific type of such device, yet it was used only by the DEA administration), but a radio system was soon established. The data sharing was far from ideal, especially due to the tardiness of the transmitters, yet its usage was beneficial for both the DEA and the BNDD.
A different, more scientific approach to technology was managed in a form of the examination of the captured substances in the chemical laboratories. At the beginning, the Administration was not in charge of their own exclusive laboratories, but rather was supported by various government offices concerned with chemical composition of drugs; they would later be conjoined into one system, under the supervision of the DEA, and characterised by the author as:

“(...) primarily responsible for performing the ballistics analyses of tablets and capsules, identifying newly-encountered compounds found in drug traffic, and conducting methods development. (...) The original chemist work force for these laboratories came from several field laboratories run by government agencies. The professional staffing of the six laboratories consisted of 36 “bench” chemists doing physical lab research, supplemented by five supervisory chemists.”

Finally, the technology that came into use was also present in forms fairly different from recording devices and laboratory glass.
With the expansion of drug trafficking, it soon became clear that the issue could no longer be monitored only by ground patrols; yet, when the idea of using aircraft in order to track the traffickers was first conceived, the DEA did not have resourses sufficient to acquire a plane. Nonetheless, the concept ended up being put into execution, mainly thanks to the retired air force pilot, simply known as “Joseph” - the Administration was granted a military assistance (an operation possible in cases of organs of the government) in a form of a plane.
The idea produced a very successful, desired outcome and, still in 1973, the DEA (or, more specifically, its Air Wing) was in possession of over twenty single-engine planes.
The beginning of the 1970s marks the start of the organised policy concerning the prevention of drug trafficking and substance abuse, as well as the elimination of already existing issues, hence the time period was discussed and focused on the most above. The description of the methods used by the assigned forces, as well as the recounting of the introduction of various substances into the human society at various stages of its development, were also conductive to understanding the mechanics of physical and mental addiction.
What is more, the depiction of both the fight against drugs and their continuous presence in the life of a man, illustrates yet another matter – the continuity of the said process. The War on Drugs is but the most popularised of its stages; as mentioned in the earlier parts of the chapter, the first ever (recorded) attempt at prohibition took place in the ancient Egypt, followed by numerous later attempts, but so did the usage of drugs, alongside with the efforts to diminish the notion of their negative effects on health in the people's consciousness (e.g. the comparison of cannabis to tobacco).
Conclusively, the mechanism is still present nowadays.
The indication for the process reoccurring in the last decades became most noticeable at the end of the twentieth century. The diagram presented below illustrates the number of deaths related to abuse of prescription opioids, as compared to heroin (diacetylmorphine) and other drugs of the same type (according to CDC Wonder):

 
The issue of the growing number of prescription opioids overdoses spiked rapidly at the end of the 1990s, together with the general number of deaths caused by related substances. Interestingly, the level of heroin usage did not increase up until over a decade later, where a slight decrease in the overdoses on the legally distributed substances can be spotted. Such interchangeability suggests a correlation between both types of opioids, the possibility of one being successfully replaced with the other as the subject of addiction.
When presented with the theory, one might argue that even though the drugs prescribed medications come from the same drug class as the illegal items, the former must have specific indications of being non-addictive, or at least less harmful than the latter, since it is sold in accordance with the law. Whereas such logic appears to be reasonable, the rationale for the pharmaceuticals as the “safe version” of opioids can be demystified by comparing the properties of both.
(The medicament used for comparison in the drug OxyContin, as the agent quoted above describes it as the most abused prescription drug in the US.)
According to the Californian drug recovery facility, New Life House:

"users seek the euphoric, pain relieving and sedative effects (...) Some possible signs of Oxycontin abuse are lethargy, stoned appearance, pinpoint pupils, constipation, loss of appetite, and lack of interest in recreational activities".   

In his book Dope Double Agent: The Naked Emperor on Drugs, author Michael Agar (2006) describes his own experience with opioids, albeit the outlawed ones. The summary of his involvement with heroin can further serve as a matter of the aforementioned comparison:

“Patrons sat along the bar like birds on a wire. I nodded at a couple I knew by sight. (...) I looked around at the empty bar stools, trying to decide where I’d sit. Then it hit me – I didn’t give a shit. In fact, I didn’t give a shit the rest of the evening – it didn’t matter what anyone said or did. It didn’t matter if I spilled my drink or not. It just didn’t matter. I was always pretty relaxed in Stryker’s, but I was even more relaxed than usual. I just didn’t have a care in the world.” (p. 173)

The focus on the sedative and calming properties of both substances reads as the most distinguishable. This comes as no surprise, since opioids are well-known for such inducing such effects, which has also been mentioned earlier in the description of FriederichSerturner's work on poppy plant.  
As the data and testimonies provided above helped establish that legally sold opioids (OxyContin) possess the same or very similar qualities as heroin (diacetylmorphine) it is important to focus on the issue of safety yet again. How is that possible that despite almost twenty thousand deaths in 2014 caused by pharmaceutical painkillers, they are still being marketed? Why is their striking similarity to delegalised substances not an indicator of them also becoming outlawed?
First and foremost, it is only logical that no substance would be marketed as a painkiller if it did not provide painkilling attributes. In this case, the medicines work by stopping certain neurotransmitters from receiving signals responsible for provoking pain-inducing reactions. Such process proves to be effective as, according to the 2014 report by Medical Magazine, all ten most popular painkillers in the USA are opioids (four of them being based on oxycodone, the substance sold primarily under the name OxyContin).
RxList, in their section dedicated to pain management, provides the explanation for such phenomenon and proof of the effectivity of opioids:

“Opioid analgesics, in general, are the strongest pain-relieving medications. The benchmark drug in this class is morphine (...) Opioids more powerful than morphine include hydromorphone (Dilaudid) and oxymorphone (Opana) [Opana has already been removed from the marked due to large scale of abuse]. But the strongest opioid in community use is fentanyl which, in its intravenous form, is 70 to 100 times more potent than morphine. Fentanyl is also available as a long-release patch (Duragesic) and as a lozenge that dissolves in the mouth (Actiq). Sufentanil is even more powerful than fentanyl, but its use, at present is restricted to the intravenous route.”

That is, obviously, not to say that the noticeable benefits patients receive from opioid-based treatment diminish the data collected on lethal overdoses or prevent attempts to restrict or control the sale.
One of such pursuits gained considerable media attention in 2019, as CDC (The US Centers for Disease Control and Prevention) presented new guidelines for the sale and indications for prescribing opioid-based medicines. As summarised by the article published on the official website for American Physical Therapy Association, the content of the guideline raised concerns among patients suffering from chronic pain, as they feared they would no longer be allowed to obtain the medication that helped them alleviate their symptoms; what is more, numerous organisations concerned with oncology (opioids are also widely used in treating pain in patients with cancer) and hematology accused the CDC of helping create circumstances in which patients would consider bribing the doctor in order to be able to acquire the drug essential in their long-term treatment. The CDC responded to the complaints by stating:

“The Guideline was developed to provide recommendations for primary care physicians who prescribe opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care (...) The Guideline is not intended to deny any patients who suffer with chronic pain from opioid therapy as an option for pain management (...) the Guideline is intended to ensure that clinicians and patients consider all safe and effective treatment options.”

According to the article, the mention of “all safe and effective treatment options” refers to non-opiod painkillers; such solution would prove to be beneficial, provided the use of the substitute substances possessed less or no risk of addiction and abuse. However, the report by Medical Magazine, as well as the data provided by RxList, remind one that the painkilling qualities of opioids are still considered the most effective. A long-time user of a certain pharmaceutical that provided them with successful pain management would also feel hesitant to trying a new, less known solution.
Likewise, one of the comments referring the article on the actions taken by the CDS helps better illustrate the issue from the perspective of the person directly concerned with it:

“I too live in severe chronic pain and have been reduced to a point that I don't sleep or want to eat so my weight has dropped to less than 100 pounds. I followed the instructions on my bottle religiously because I needed them to live a somewhat normal life. It is sad some choose to abuse but why are we punished for it. (...) The numbers are skewed and docs know who does and doesn't abuse we are monitored like children. WE ARE JUST AS IMPORTANT as those who choose to abuse or abuse street drugs...where is the compassion for us..the ones who can't be "fixed"?”

All the factors detailed above seem to have created a paradox that bars both parties – those that developed drug dependence because of improper usage and those that need certain medicines for legitimate causes – from receiving a helpful, safe solution to their dilemma. While opioids constitute a huge percentage of prescription misuse, and overdoses, no resolution has yet been provided that would arrest or at least reduce the issue without doing disservice to patients with chronic pain.
The purpose of the chapter was to not only familiarise one with the history of substance abuse, its characteristics in reference to specific drugs, but also to introduce the concept of prescription abuse and the concern of the shared origins of specific pharmaceuticals and illegal substances. Therefore, because of its purpose, the chapter does not detail specific cases, but simply helps illustrate the general issue.

17 August 2020

Postcolonial criticism in Ann Radcliffe's 'The Italian'

The name Ann Radcliffe rings a familiar note for everyone interested in Gothic literature -  however, she is not a figure popular only among fans of the particular genre. Having utilised her vivid imagination and exceptional linguistic skills, Radcliffe became one of the most notable authors in the 18th century. Nonetheless, despite her wide recognition still being mainly associated with the realm of the supernatural, the versality of her abilities allowed her to appropriate eclectic elements of different kinds of fiction into her own work.
Born in London in the second half of the 18th century, the author grew up during the times of the birth and development of Gothic literature. Her interest in writing, however, seems to be circumstantial rather than influenced by the artistic environment of her time. As a wife of a journalist who used to spend most of his day at work, to distract herself from indifference and loneliness, Mrs Radcliffe picked up the pen and began to write short stories, and later longer pieces, of her own (with the encouragement of her husband). 
Although the aforementioned talent of Ann Radcliffe is broadly known, apart from the details of her beginnings as an author, not much can be acknowledged regarding the writer's personal life. Not only did Radcliffe not strive to become a public persona; she was also a deeply enigmatic figure, keen on maintaining her privacy, to the point of desperately seeking seclusion. 
Due to the rather poor level of understanding mental conditions at the time, as well as numerous rumours steaming from the public's desire to learn more about the secretive Radcliffe, the author's sudden disappearance from the literary scene almost three decades before her death, provoked the widely believed assumption that she had fallen into insanity as a result of the nature and content of her own writing. 
No biographer was ever able to obtain the amount of information sufficient to either confirm or disprove such innuendos – one can only assume that it was Radcliffe's reserved personality that she chose to live in accordance with, meaning she would not continue her literary career (although generally stripped from fame and public appearances) as a result. The cause of her death cannot be asserted with certainty as well, albeit respiratory problems seem to be the option that is universally agreed upon.
Nevertheless, despite Ann Radcliffe's ambiguous persona, her literary work remains popular to this day, and attained universal acclaim (Radcliffe is regarded as one of the pioneers of her genre), influencing several later authors, not necessarily associated with Gothic fiction.
But what would make work like Radliffe's, so strongly linked with one particular style and narrative, able to fall into a different category? How did the creative versality manifest exactly? To learn the answer (and appreciate the writer's skills even more) one should analyse „The Italian”, Radliffe's second-to-last novel, published by the end of the 18th century. 
„The Italian” is usually regarded as a controversial position in the author's bibliography, as a result of a supposed anti-Catholic sentiment included on its pages. Whether such claim is true, is best left for the reader to decipher and judge; the setting and the subject matter of the novel, however, especially in the „Introduction” part, serve as a fine example of genre-fusion. 
While schools of criticism do not necessarily form a different literary genre, applying the thought usually related to one particular genre into another – where possible – can provide a deeper or disparate understanding of the topic. Such is the case with the discussed work of Ann Radcliffe, when it is being examined from a postcolonial perspective. 
The subject of the analysis is the „Introduction”, as it portrays the disparities in understanding certain behaviours by two separate cultures. 
As the title of the novel suggests, the story takes place in Italy, more specifically, in Santa Maria del Pianto church, in the second half of the 18th century (the timing, yet again, is set in the age of the highest popularity of the Gothic fiction, but also during the time of the British Empire being one of the world's greatest powers, and still governing the United States). 
In short, the fragment discusses the experience of English tourists visiting the church together with their Italian friend. While, obviously, Italy was not ruled by Great Britain, one can assume the choice of the location (whether conscious or not – despite the discussed example of literary diversity, „The Italian” is still considered to be Gothic fiction, and the reader can simply conclude that Italian architecture provided an appropriate setting for such story) was supposed to be a metaphor for the great influence of colonialism; even those not affected by it in a traditional sense, can still experience its authority. 
The postcolonial perspective can first be applied when the travellers spot a figure they believe is extraordinary for the place (the church belongs to a convent):

„Within the shade of the portico, a person with folded arms, and eyes directed towards the ground, was pacing behind the pillars the whole extent of the pavement, and was apparently so engaged by his own thoughts, as not to observe that strangers were approaching. He turned, however, suddenly, as if startled by the sound of steps, and then, without further pausing, glided to a door that opened into the church, and disappeared.”

A monk the group encounters a while later calmly explains that the person they have seen is an assassin. 
The Englishmen have trouble believing so and do not understand how a criminal is able not only to not be locked up in jail, but also that the monk is not troubled by such situation, and, in fact, seems to be content with it.
Such surprise does not show disparities in morality between the tourists and the monk (the Italian man travelling with the English is also not startled by the presence of the assassin), as they both agree that he is a criminal. However, while the tourists show indignation at the fact he is allowed to live with the convent, the locals explain their perspective.
No one can be harmed inside the church, and – as they saw the assassin as a human first, and as a criminal later – they provided him with the shelter he was looking for. The Italians are shocked the English when they explain that the criminal is provided with food. While one can agree with the tourists at this point, especially after learning that the monks feed the man because of the seemingly ridiculous assumption that the city would die out otherwise, since the assassinations are so frequent, such attitude represents the locals' beliefs. 
The situation can be perceived by the reader as a symbol for how the colonised societies are generally made to follow a justice code that is not easily understood and foreign to them. It also portrays the metaphorical colonists as those who abide justice, and the colonised as the people that are guided by their feelings and beliefs.
The Englishmen are then left speechless, and their Italian friend steers their attention to a different part of the building:

„'But observe yonder confessional,’ added the Italian, ‘that beyond the pillars on the left of the aisle, below a painted window. Have you discovered it? The colours of the glass throw, instead of light, a shade over that part of the church, which, perhaps, prevents your distinguishing what I mean!'”

The tourists study the confessional in silence for a moment, but when they finally speak up, they seem to come back to the previous discussion.
They notice that the door reminds them of those the assassination passed through earlier. The entire place also supposedly looks so scary that it would undoubtedly frighten any criminal. 
Therefore, yet another analogy between real colonialism and the fictional story can be drawn. 
There colonised places can be, undeniably, interesting, charming the foreign visitors with their initially mysterious and ambiguous nature; they can also serve a specific purpose, important for the locals (just like a confessional is where a confession takes place). The colonialists, however, appear to fail to acknowledge the characteristics of the land for what they are, and instead compare them to what they know from their homeland. As much as such reaction can be understandable (seeking comfort in what is known), what is suggested in the text („‘Well, but what of this confessional?’ enquired the Englishman. ‘The assassin entered it!’”) is the Englishmen' immediate negative reaction to the novelty. This, yet again, symbolises that, in the mind of the colonisers, the role of law – the law that they practise – is what dictates their views on the surroundings.
Finally, the Italian yet again tries to draw his friends' attention to the confessional itself. He reveals that it has not been used in a few years, but that he would like to share a story about it and certain „extraordinary circumstances” connected to it. 
The group agrees, but one of the tourists mentions that, for what he knows, the confession should always remain a secret between the believer and the priest. The Italian agrees, but indicates that there are cases in which what has been said can be revealed and that, when he shares the story, no one will be surprised or irked by this fact. 
The similarity that can be drawn between actual colonisers and the characters in the story is, as in the previously mentioned cases, that the division that emerges is connected to the original set of beliefs of both parties, although this time the colonisers are surprised at the advancement that the locals have made. It should be noted that in the story, the Englishmen are not eager to object or refuse to learn whatever their friend wants to share – they simply note that, according to them, such secrets should not be revealed, but are open to discovering the circumstances in which the rule does not apply. In reality, the colonised also did possess things, usually material, like fabrics and spices, that the „guests” find valuable or interesting, and were willing to learn more about them.
To summarize, the skills and literary talent of Ann Radcliffe allowed her to create a novel that undeniably belongs to the world of Gothic literature, yet its specific parts, when analysed separately, create an excess of diverse meanings and ways in which the work can be understood. Nowadays, when the ear of classically understood imperialism has come to an end, the initial part of „The Italian” provides the reader with an opportunity to understand the issue first hand – as written about by a person who lived in the times of interest. 
Certainly, postcolonial criticism is only one of the ways in which the novel can be deconstructed and explained. It might be, however, one of the most interesting and intriguing interpretations, thanks to the visible division between „us” and „them” and the time of setting, as well as the original creation. 

3 May 2020

New historicism [definition, historiography]

1. The "new":
New historicism includes the surroundings of the author, the influences they might have been subjected to in its focus, instead of dealing only with the content of the work, the data included in it which is characteristic to the traditional approach. The personal opinion of the critic does not need to be omitted.

2. Analysing literary works from such perspective:
The literary work should be criticized and studied not as a single entity, but the analysis requires taking into consideration the author themselves (their personality, beliefs, personal history), as well as the influence of the environment on the creation of the literary work, and the critic's subjective view.

3. Literature and historiography
Historiography studies the methods various historians used to describe historical events in their work - this might be done for the purpose of discovering different perspectives, and revealing how and whether the accounts change due to time frame, the author's origins, etc. Therefore, a part of historiography - works of literature describing historical events - is interchangeably included in literature itself, and can be interpreted and analysed from a chosen literary perspective. 

16 April 2020

Reader-response theory [definition, explanation]

Reader-response theory differs from the "standard" view on a literary work in such a way that it changes the way one should look for the intended meaning. Whereas it is often implied that a work of literature conveys a specific message or implication regardless of the reader's reaction to it, Iser argues that - when looking for the actual implication - the focus should be put not on the work itself, but on the reader.
Therefore, such approach conveys the idea that the reader is not just a mere consumer of the text, but rather plays a significant role in it becoming truly complete. According to Iser, reading is more than just familiarizing oneself with the literary work in order to decipher its objective, but instead should be understood as a conscious way of creating the meaning. Although reader-response theory does not deny the existence of the author's indented concept, it encourages attributing the factual meaning to the reader's subjective opinion and interpretation. Such method then allows creating numerous perspectives on and explanations of the same text, thus clarifying the concept of "completing" it - while it might be complete in its physical form, it is the reader's personal interpretation that is the actual, final part of concluding the literary work.

10 December 2019

Exemplary summary

Satrapi's work was first recognised in the US in 2003 - first as a series of articles, then as a full bok - and praised as a didactic statement of a middle-eastern woman who experienced the atrocities of war and prejudice first hand. "Persepolis", however, is not an ordinary book not only because of its content; a huge part of the story is expressed by drawings, which places it among the various categories of graphic novels. The author herself can also be categorised as distinctive. Defying the stereotype of an Iranian female, Satrapi reveals her background as a double graduatee (in Iran and in France), fluent in several languages, who comes from a fairly liberal family. Yet, despite her skills, it was not until she met a colleague whose work encouraged her not only to translate her memories and stances into a material form but also to abandon the notion of autobiography as a plain text riddled by dates. Satrapi's persistence and creativity, however, can not be diminished in any way, as "Persepolis" was first released without any promotion or any similar assistance from the publisher; it was the merit of her work that touched its readers that the work was solely popularised by the word of mouth. The non-conventional seems to be a returning theme in Satrapi's life - both as a human being and as an artist. It is only fair to describe what the reader can expect from the book itself as falling into the line. The simplicity of the graphic aspect of "Persepolis" remains in contrast with its written content, filled with a raw description of the Iranian Revolution and unrestrained channelling of emotions and personal struggles. And the biggest surprise of all? The book is unavailable for its potential readers in Iran due to the unpolished and uncensored depictions of the powers governing the Iranian society - the only translation into Farsi has never been authorised, and can only be obtained illegally.

12 March 2019

Henri de Toulouse-Lautrec and Jane Avril

Henri de Toulouse-Lautrec knew how to use his genius and characteristic style of drawing not only to draw attention to himself, but also to commemorate others - especially his muse, Jane Avril.
Born Jeanne Beaudon, the dancer grew up under the care of her abusive mother (she never learnt the true identity of her father); the mistreatment lead to the development of neurological problems in Avril. However, her stay in the Salpêtrière clinic helped the young patient discover her talent and passion for dancing.
As a professional, Jane Avril was appreciated by various representatives of the Symbolist movement in poetry, but it was Arsène Alexandre, a French art critic, who noticed her unconventional relationship with Toulouse-Lautrec.
The painter's acknowledgement of Avril benefited both artists: after unsuccessful beginnings, Lautrec became a well-known poster artist, and the beauty and eye-catching charm of the dancer was captured not only for the late 19th century Parisians, but also the whole world.
Nevertheless, it is worth mentioning that Lautrec's paintings of Avril differ considerably from his posters: the latter depict a "graceful, light, a little mad, pale" woman, as Alexandre notes, while the former detail a pensive and older figure. The way the dancer was portrayed on the canvas helped establish her persona as an independent and self-sufficient woman, whose grace can still be regarded today.

22 December 2018

What role does creativity play in modern education? [short example essay]

Creativity plays a huge role in the modern education process. Whether it is teachers choosing unorthodox methods of sharing their knowledge, or pupils trying unconventional ways of acquiring information, an innovative approach is always beneficial.
To begin with, state-of-the-art technology provides teachers and lecturers with an opportunity to educate young people in a more creative and engaging way. A monotone and repetitive talk can be replaced with watching a topic-related film or browsing the Internet together in order to find the desired information; such activities are, undoubtedly, present in every student's day-to-day life and will transform their academic experienced into a pleasantly spent time, instead of a dull necessity.
Yet, it is not just teachers that can use creativity to improve the quality of the class. Thinking "outside of the box" is certain to make an individual presentation or a group project more enjoyable - both for the teacher and the classmates - and have an impact on the final grade. Possibly, it can even draw the pupils' attention to certain topics and issues, therefore broadening their knowledge even more.
Finally, creativity proves to be helpful not only during the class, but also when studying at home. Homework does not necessarily mean hours spent reading textbooks - a person that is not afraid to use their imagination can surely find numerous ways of looking for the needed information that usually are less time-consuming and might provide them with even more valuable knowledge.
The modern world creates various opportunities for those that desire to learn or share what they already know, if only one is willing to try a different, previously unavailable approach, certain to improve one's academic performance.

7 December 2018

What role does music play in life? [short example essay]

Just as there are many different genres of music, this branch of the arts might also serve various purposes. From helping a person achieve a well-deserved rest to becoming a valuable source of income, music provides numerous ways for it to be enjoyed.
First of all, listening to music can be relaxing or help one calm down - there are many songs and albums created specifically for this purpose. The biggest advantage of such a way of resting is that there is usually no need to take any medicaments to alleviate the stress it is important to remember, however, that if painkillers or other drugs have been prescribed, they should always be taken.
Additionally, music provides an opportunity for a person to be met with a cathartic experience. It might seem similar to relaxing, but requires one's own effort - creating lyrics and songs - rather than simply listening to other artists. It is a fine method of confronting negative emotions that prevents one from upsetting others or harming oneself.
Lastly, as music is highly commercialised these days, composing one's own pieces might not only help cope with personal struggles, but also become a way of making money. Surely, not every musician is talented (or lucky) enough to sell millions of records worldwide, but it should not discourage anyone from trying to advertise their own creations the alternative scene is also popular, especially among the young, and can provide a chance for wider recognition.
Beyond any doubt, music serves numerous purposes, and can be used as a means of improving a person's well-being - both psychological and economic - without unnecessary medical or other external intervence.

30 November 2018

The role of creativity in a person's life [short example essay]

Usually associated with ar or innovative inventions, creativity can also come in handy in day-to-day life. This particular trait can definitely help one in a variety of circumstances, from improving work performance to discovering uncomplicated methods of self-help.
Many people, especially those who have struggled to find their current job, are afraid of losing the position, and thus do not consider taking any risks or carrying out their ideas of how to increase their chances of promotion. While such an attitude is understandable, not taking advantage of whatever capabilities a person might have - in this case, creativity - is sure to prevent them from progressing, which can have a negative influence on both their career and mental well-being.
Alarming and potentially dangerous consequences of numerous situations can also be alleviated by an original approach. From actions as simple as figuring out how to open a tightly sealed jar to evading a car crash, one should always consider imagination an important resource.
Finally, a person who feels sad and distressed can easily count on their creativity to help them break out of their bitter mood. Obviously, one should always seek professional help if it is needed, but it is important to remember that something almost effortless - like a new hair colour - can make a day better.
The work "resourcefulness" might have negative connotations, but when used to describe the simple ways of advancing the quality of someone's daily life, nobody should refrain from using their creativity to benefit themselves or others.

9 November 2018

Is studying history a waste of time? [short example essay]

Nowadays, people - especially the young - are so focused on their day-to-day life and concerned with their future that they minimalise the importance of the past, thus not paying much attention to history lesson. Such an approach, however, is likely to prevent one from acquiring valuable knowledge, affecting both one's academic and personal chances of success.
It is often said that whoever does not know history is sure to repeat humanity's past mistakes. the belief appears to be true, as the world is continuously troubled with military conflicts, as well as social and economic issues; the reasons for said disturbances, more often than not, happen to be very similar to those that sparked past conflicts.
Studying history can also be very helpful if a person desires a stable job or a fruitful career path. Positions such as an archaeologist or a politician are usually well-paid and respected, but unattainable without a higher level of historical knowledge.
Last but not least, past events have made every person who they are today - this tendency is especially visible in regions that have been damaged by wars or troubled by various other conflicts. Familiarising oneself with the origins of such situations can become a valuable asset on one's path to self-discovery.
Being preoccupied with living in the moment should never be an obstacle on a person's path of rediscovering the past. What has already happened can undeniably happen again, and whoever is familiar with history can certainly use it to their advantage.